Large macrolide drugs are used in the treatment of respiratory diseases caused by gram positive bacteria and gram negative bacteria. Large macrolide drugs include clarithromycin, azithromycin, erythromycin and others. Large macrolide drugs are very popular due to their efficiency and safety. Large macrolide drugs have a large lactone ring containing 12 to 14 atoms .Large macrolide drugs inhibit the bacterial protein synthesis by interrupting the ribosome functioning. Clarithromycin and azithromycin are the derivatives of erythromycin. Large macrolides drugs inhibit the bacterial protein synthesis by reversibly binding to the 50S subunit of ribosome. Bacterial growth is inhibited by the large macrolide drugs as they separate the peptidyl transfer RNA from the ribosome during the elongation phase. Large macrolides drugs are mainly used in therapy for local and systemic infections. In veterinary medicines, large macrolide drugs are used for treatment of upper respiratory tract infections, bacterial enteritis, bronchopneumonia metritis, pyodermatitis, arthritis and other urinary tract infections. Large macrolides drugs are effective against most of the aerobic and anaerobic gram-positive organisms.
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Large macrolide drugs are absorbed from the gastrointestinal tract and are distributed well in the tissues. Large macrolides drugs are concentrated in macrophages. They accumulate in the spleen, kidney, liver and lungs.
Large Macrolide Drug Market: Drivers and Restraints
The growing prevalence and recurrence of bacterial infections is expected to be the major factor driving the growth of the large macrolide drug market over the forecast period. Increasing number of drug resistant bacterial strains is also expected to drive the growth of the large macrolide drug market. Growing geriatric population is also one of the factors expected to surge the growth of the large macrolide drug market. The large macrolide drugs have many advantages over traditional medicines, which has increased their demand across the globe. Large macrolide drugs are safe owing to which their demand tends to double in the coming years. The side effects of large macrolide drugs such as gastro intestinal disturbances, e.g., nausea, diarrhea, and vomiting, is projected to restrain the growth of the large macrolide drug market over the forecast period.
Large Macrolide Drugs Market: Regional Outlook
Geographically, the global large macrolide drugs market is segmented into North America, Latin America, Europe, Asia-Pacific excluding Japan (APEJ), Japan and the Middle East and Africa (MEA). North America is expected to be dominant regional market for large macrolide drugs owing to high prevalence of the bacterial diseases. The large macrolide drugs market in Asia Pacific is expected to grow at a significant CAGR due to presence of large population. Europe is expected to hold second large share in the global large macrolide drugs market throughout the forecast period.
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Large Macrolide Drug Market: Overview
Clarithromycin and azithromycin are the derivatives of erythromycin. Others include spiramycin and telithromycin. They all are common types of drugs that are anti-bacterial and are used in the treatment of respiratory bacterial infections. Based on the distribution channel, large macrolide drugs are distributed by hospital pharmacies, retail pharmacies, drug stores, and online pharmacies. They are effective against bacterial infections.
Large Macrolide Drugs Market: Key Players
The global market for large macrolide drugs is highly fragmented. Examples of some of the key players operating in the global large macrolide drugs market are Abbott, Pfizer limited, Merck & co Inc., Sun Pharmaceutical Industries Limited, and Attix Pharmaceuticals, among others.
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